Lipid-Based Nano Formulation Approach to Target Brain for the Management of Tuberculosis through Intranasal Delivery: Formulation Development and Evaluation
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Formulation and ex vivo Evaluation of Solid Lipid Nanoparticles (SLNS) Based Hydrogel for Intranasal Drug Delivery
Risperidone (RISP) is an antipsychotic agent and has low water solubility and nontargeted delivery results in numerous side effects. Hence, an attempt was made to develop SLNs hydrogel for intranasal delivery of RISP to achieve maximum bioavailability and reduction of side effects. RISP loaded SLNs composed of 1.65% (w/v) lipid mass were produced by high shear homogenization (HSH) coupled ultra...
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PURPOSE Agomelatine is a novel antidepressant drug suffering from an extensive first-pass metabolism leading to a diminished absolute bioavailability. The aim of the study is: first to enhance its absolute bioavailability, and second to increase its brain delivery. METHODS To achieve these aims, the nasal route was adopted to exploit first its avoidance of the hepatic first-pass metabolism to...
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in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...
15 صفحه اولEvaluation of a nanosuspension formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers
This study aimed to determine the aerosolization behavior of a nanodispersion of budesonide, prepared using microfluidic reactors. The size and morphology of budesonide nanoparticles were characterized by photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM). Processing/formulation parameters for formation of the nanoparticles were studied to determine their effects o...
متن کاملEvaluation of a nanosuspension formulation prepared through microfluidic reactors for pulmonary delivery of budesonide using nebulizers
This study aimed to determine the aerosolization behavior of a nanodispersion of budesonide, prepared using microfluidic reactors. The size and morphology of budesonide nanoparticles were characterized by photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM). Processing/formulation parameters for formation of the nanoparticles were studied to determine their effects o...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Education and Research
سال: 2020
ISSN: 0019-5464
DOI: 10.5530/ijper.54.2s.75